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Poll

How confident are you in using the AAD decision tree when managing suspected AAD?

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Not confident
   
A little confident
   
Moderately confident
   
Extremely confident
   

Tutorial

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Poll

Which of the following aspects of care for AAD would you like more support with?

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Effective care partner communication
   
Supporting care partners emotionally
   
Pharmacological treatment options
   
Non pharmacological/psychosocial treatment options
   

Tutorial

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Poll

In a typical month, what proportion of the patients you encounter experience agitation associated with Alzheimer’s dementia?

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<20%
   
20–50%
   
51–80%
   
>80%
   
 
Prevalence of agitation in Alzheimer's dementia
Impact of agitation in Alzheimer's dementia on people living with dementia and their care partners
How to recognize and diagnose early-stage agitation in Alzheimer's dementia
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Alzheimer's Disease and Dementia, Neurodegenerative Diseases, Psychiatric Disorders CE/CME accredited

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A relaxed discussion between two faculty focussed on real world clinical issues. Useful tips below will show how to navigate the activity. Join the conversation. Close

Let’s talk about agitation in Alzheimer’s dementia: Prevalence, behavioural symptoms and reaching a diagnosis

  • A practice aid is available for this activity in the Toolkit
  • Downloads including slides are available for this activity in the Toolkit
Learning Objectives

After watching this activity, participants should be better able to:

  • Explain the prevalence of agitation in Alzheimer's dementia and the circumstances in which it may occur
  • Summarize the symptoms of agitation in Alzheimer's dementia and their impact on patients and care partners
  • Discuss how to identify early-stage agitation in Alzheimer's dementia and reach a diagnosis
Overview

In this activity, a gerontological nurse practitioner and a family care partner discuss the prevalence and typical presentation of agitation at different stages of Alzheimer’s dementia. Early recognition and diagnosis is important; it enables the implementation of best practice management strategies to reduce the overall burden of agitation for people living with Alzheimer’s dementia and their care partners.

This activity is jointly provided by USF Health and touchIME in collaboration with the Gerontological Society of America (GSA).

Target Audience

This activity has been designed to meet the educational needs of Alzheimer’s disease specialists, neurologists, psychiatrists, primary care physicians, specialist nurse practitioners and physician assistants involved in the management of people living with dementia associated with Alzheimer’s disease.

Disclosures

USF Health adheres to the Standards for Integrity and Independence in Accredited Continuing Education. All individuals in a position to influence content have disclosed to USF Health any financial relationship with an ineligible organization. USF Health has reviewed and mitigated all relevant financial relationships related to the content of the activity. The relevant relationships are listed below. All individuals not listed have no relevant financial relationships.

Faculty

Dr Carolyn Clevenger discloses: Advisory board or panel fees from BrainCheck, Inc., Eli Lilly and Company, and Otsuka America Pharmaceutical Inc.

Ms Kathleen Rhyne has no financial interests/relationships or affiliations in relation to this activity.

Content reviewer

Danielle Walker, DNP, APRN, AGNP-C has no financial interests/relationships or affiliations in relation to this activity.

Touch Medical Contributors

Christina Mackins-Crabtree has no financial interests/relationships or affiliations in relation to this activity.

USF Health Office of Continuing Professional Development and touchIME staff have no financial interests/relationships or affiliations in relation to this activity.

Requirements for Successful Completion

In order to receive credit for this activity, participants must review the content and complete the post-test and evaluation form. Statements of credit are awarded upon successful completion of the post-test and evaluation form.

If you have questions regarding credit please contact cpdsupport@usf.edu 

Accreditations

Physicians

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through a joint providership of USF Health and touchIME. USF Health is accredited by the ACCME to provide continuing medical education for physicians.

USF Health designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Advanced Practice Providers

Physician Assistants may claim a maximum of 1.0 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 CreditTM from organizations accredited by ACCME or a recognized state medical society.

The AANPCP accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM by ACCME-accredited providers. APRNs who participate will receive a certificate of completion commensurate with the extent of their participation.

Date of original release: 18 July 2024. Date credits expire: 18 July 2025.

If you have any questions regarding credit, please contact cpdsupport@usf.edu

This activity is CE/CME accredited

To obtain the CE/CME credit(s) from this activity, please complete this post-activity test.

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  • A practice aid is available for this activity in the Toolkit
  • Downloads including slides are available for this activity in the Toolkit

Topics covered in this activity

Alzheimer's Disease and Dementia / Neurodegenerative Diseases / Psychiatric Disorders
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touchIN CONVERSATION
Let’s talk about agitation in Alzheimer’s dementia: Prevalence, behavioural symptoms and reaching a diagnosis
1.0 CE/CME credit

Question 1/5
Confusion, pain and discomfort can all trigger agitated behaviour in people living with Alzheimer's dementia, but what is the root cause of AAD?

AAD, agitation in Alzheimer’s dementia.

The psychological symptoms of dementia are likely to have a distinct neurochemical and neurobiological basis. Available evidence suggests that agitation in Alzheimer’s disease is associated with a serotonergic deficit, relatively preserved dopaminergic function and compensatory overactivity of postsynaptic noradrenergic neurons. 

Reference

Liu KY, et al. Ageing Res Rev. 2018;43:99–107.

Question 2/5
A care partner tells you they needed their daughter's help because their partner with Alzheimer’s dementia refused to get dressed one morning. What would be helpful for you to do as a healthcare professional to support the care partner and their loved one living with Alzheimer’s dementia?

PLWD, person living with dementia.

The first step in managing agitation is to properly define and assess the specific behaviours reported. These assessments should include information about frequency, duration, whom it affects, potential triggers, reinforcements of the behaviour and severity. It is important to obtain specific examples to determine if consensus exists about what has been witnessed. The degree of risk posed to the patient and others by the specific behaviour should also be assessed.

Reference

Wolf MU, et al. Continuum (Minneap Minn). 2018;24:783–803.

Question 3/5
Your 76-year-old male patient with Alzhemier’s dementia has recently been showing signs of agitation. His care partner (his wife) would like to know more about the potential impact of agitation on her husband. What information would you provide?

AAD, agitation in Alzheimer’s dementia.

AAD is associated with many negative outcomes. These include accelerated disease progression, physical and mental health deterioration, functional decline, higher risk of admission to LTCFs and poor quality of life. Notably, agitation is one of the most important factors that impacts whether a PLWD is placed in a LTCF. 

Abbreviations

AAD, agitation in Alzheimer’s dementia; LTCF, long-term care facility; PLWD, person living with dementia. 

Reference

Gerontological Society of America. Insights and Implications in Gerontology. August 2023. Available at: https://bit.ly/3HbJQyE  (accessed 2 July 2024).

Question 4/5
A care partner is becoming increasingly distressed and anxious that their behaviour may be exacerbating symptoms of agitation in their loved one who has Alzheimer’s dementia. What advice do you give them?

Most of the time, agitation and anxiety happen for a reason. When they happen, it is important to try and find the cause. The Alzheimer’s Association provides tips on how to prevent and reduce agitation and these include: creating a calm environment; avoiding environmental triggers; monitoring personal comfort; simplifying tasks and routines; and providing opportunities for exercise.

Reference

Alzheimer’s Association. Available at: www.alz.org/help-support/caregiving/stages-behaviors/anxiety-agitation (accessed 2 July 2024).

Question 5/5
What role does the AAD decision tree play in supporting clinical practice?

The AAD decision tree for guiding the management of AAD outlines several steps that should be followed for assessing and managing AAD, starting with ongoing assessment for the emergence of symptoms, differential diagnosis, and nonpharmacologic and pharmacologic treatment approaches. It is complementary to the Describe, Investigate, Create and Investigate (DICE) framework, which can be used to creatively develop individualized care plans to proactively address care recipient needs and inform care interactions. The decision tree includes an optional step to assess the severity and frequency of the agitation behaviour.

Abbreviations

AAD, agitation in Alzheimer’s dementia; IPA, International Psychogeriatric Association.  

Reference

Gerontological Society of America. Insights and Implications in Gerontology. August 2023. Available at: https://bit.ly/3HbJQyE  (accessed 2 July 2024).

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